Improved gastrointestinal tract health
Flavoring
Pro-Kolin Advanced contains new and improved flavorings for dogs (liver) and
cats (chicken). Both flavorings are artificial, contain no proteins or allergens,
and can be used in animals with known hypersensitivity.
Directions for use
• Easy to use syringe
• New and improved formula
• New, highly palatable, improved flavoring –
different tastes for dogs and cats!
Administer directly into the mouth, for as long as
necessary. Pro-Kolin Advanced can
be given up to three times daily, depending on
the severity of the condition.
Probiotics
Pro-Kolin Advanced contains the EU-registered probiotic bacterium Enterococcus faecium
(NCIMB 10415) 4b1707. Enterococcus faecium in Pro-Kolin Advanced has been shown to survive passage
through the digestive tract for maximum efficacy.
Prebiotics
Preplex® prebiotics is a combination of two different types of prebiotics –
fructo-oligosaccharides (FOS) and acacia (gum arabic), which is unique
to Protexin Veterinary. This combination ensures that Pro-Kolin Advanced
stimulates the growth of beneficial bacteria in different areas of
the digestive tract:
Initial part of the large intestine – FOS reach the large
intestine intact, as they are not absorbed by enzymes in the small
intestine. In the large intestine, some beneficial bacteria (Bifidobacterium
spp. and Lactobacillus spp.) readily ferment FOS, leading to
an increase in their number. Since FOS have a low molecular
weight, they are utilized in this part of the large intestine.
End part of the large intestine – Gum arabic has a complex
branched structure and ferments more slowly in the end part of
the large intestine.
Pectin
Pectin belongs to soluble fibers that rapidly
ferment in the large intestine. Simultaneously with its action
as an effective prebiotic, pectin is also known for its soothing
effect on the intestinal mucosa.
Pro-Kolin Advanced
Psyllium
Psyllium belongs to soluble dietary fibers and has the ability to absorb
excess water in the digestive tract, forming a viscous, gel-like
substance. This increases the viscosity of the stool, which helps
soothe and normalize bowel transit time.
Binders
Pro-Kolin Advanced contains pharmaceutical
grade clay, which acts as a binder
and supports normal
digestive functions. Different
forms of clay have different properties,
which affect their ability to
absorb and adsorb:
Absorption – excess fluids in the
gastrointestinal tract enter the
clay molecules.
Adsorption – the ability to bind
compounds, bacteria, viruses, and
enterotoxins to the outer surface of
the clay molecules.
The use of a combination of kaolin and montmorillonite provides an optimal balance
between absorption and adsorption and offers a dual benefit for the animal.
Beta-glucans
Beta-glucans, especially those with 1,3/1,6 linkages in their chemical structure, have been shown
to stimulate natural immunity. Immune cells, such as macrophages, have dectin-1
receptors that recognize and respond to beta-1,3/1,6-glucans, leading to
increased antimicrobial activity, enhanced cellular defense, and improved resistance
to diseases.4,5
Taurine
Contained only in Pro-Kolin Advanced for cats
An essential amino acid for cats and is necessary for maintaining many
normal physiological processes, including (but not limited to) vision, digestion,
heart muscle function, and maintaining a healthy immune system. Home-made,
monotonous diets, which may be recommended for cats with digestive
disorders, are often poor in taurine. Pro-Kolin Advanced for cats provides a source for
maintaining taurine levels during periods when such diets are recommended.
Clinically proven
Pro-Kolin Advanced is the first product of its kind with clinically proven efficacy. In a study
of 148 dogs with acute diarrhea, Pro-Kolin Advanced significantly improved the clinical picture compared to
those treated with placebo.
Weight Quantity Frequency
Pro-Kolin Advanced 15ml & 30ml
<5kg 2ml Twice daily
5-15kg 3ml Twice daily
15-30kg 5ml Twice daily
>30kg 7ml Twice daily
Pro-Kolin Advanced 60ml
25-35kg 6ml Twice daily
35-45kg 8ml Twice daily
>45kg 10ml Twice daily
